Since we are almost done with Spider-Verse (god awful event, Slott is the worst, so on) I'm really hoping see a boxset or something devoted to it now. Hell, you can still keep it 616 if you wanted with some of the stay overs from the crossover
2099 needs a huge update, as usual, Spider-Gwen is getting a ton of buzz, Spider-Woman got a ton of buzz earlier and has a new ongoing and could do with an update, and throw in Morlun for a villain.
Sure, no Peter, but he isn't wearing anything different from his normal outfits.
Maybe top it off with a Spider-Noir and a May Parker 2 pack at TRU?